Just a tidbit from an interesting experiment. No one seems to know yet how calorie restriction (CR) extends life, if it even does in humans, though it can in mice, according to many experiments.
Now, it turns out that CR mice eat in a different pattern than do mice that eat almost all they want (the mice in this experiment were a bit restricted compared to the usual ad libitum-fed mice, so they were not quite pigging out). The CR mice ate in bursts rather than nibbling continuously. The ad libitum mice nibbled all day.