Arthur De Vany's Evolutionary Fitness
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Gene Expression
Active Genotype
Recent articles
Activegenomics
Aug 23, 2010
We have nutrigenomics---the study of the effect of nutrients on gene expression---and metabolomics---the study of the whole of the metabolic activators circulating in the body. The idea of functional food or nutraceuticals comes from these areas of study. They are not close yet to achieving the level of knowledge required to fulfill the ideal of prescribing nutraceuticals since they have only partial maps of the genetic pathways and the combinatorial aspects of the gene/nutrient interactions, but some sensible warnings, particularly regarding excessive nutrient intakes in childern have been established.
I want to coin a name---activegenomis---for the next field in the study of gene expression and epigenetic factors. Activegenomics studies the full range of alterations in gene expression caused by activity. That is the only way one can seriously address the contemporary problem of how the evolutionarily stable active genotype can promote a healthy expression of that genotype in a world where being inactive does not threaten survival.
Reproduction: My Little Cactus
May 27, 2010
This beautiful little cactus in my yard is spending about 30% of its energy to reproduce.
Two Sets of Genes
May 17, 2010
Not only do we have our own DNA, we also have the DNA of our mitochondria. I think the mitochondria may be more important in terms of health and longevity.
Critics of the Paleolithic Diet Don't Know Their Nutrigenomics
Apr 27, 2010
A Paleolithic diet is not a fad, which is what many nutritionists like to call it. Of course, this absolves them of having to present evidence, of which there is little, or to mischaracterize the diet in ways that make it appear foolish. If the critics knew or understood nutrigenomics, they would know better.
Another Strike Against High Glucose
Jan 17, 2010
A key element of the Evolutionary Fitness approach to health is to keep glucose levels in the body low. Glucose alters gene expression in a profound way because it is a substance that was comparatively rare during the evolution of our genes.
Identical Genes (Almost), Different Bodies
Dec 21, 2009
This picture of identical German twins is amazing. You can see in their faces that they are identical, but one is a runner and the other is a weight-lifter and they could not look different if they were from different planets. Gene expression is involved.
Cellular Autophagy
Dec 21, 2009
Autophagy (self eating or consumption) is a crucial process in the cell. The cell consumes and recycles damaged internal material; this is an energy sparing process and important for scavenging old and damaged material within the cell